During pregnancy, expectant mothers can and should ask their doctorsif there will be any harm to my baby when using any medication. They should consult their doctor before using any medication other than folic acid, vitamin and iron supplements used during pregnancy prescribed by gynecologists or family physicians. The category of pregnancy and breastfeeding is written on the package inserts of the medicines. Group A supportive therapies are generally prescribed during pregnancy. In some clinical situations, group B drugs may also be preferred. Group C and D medications are administered in cooperation with the doctor and patient according to the benefit and harm ratio. Until the 31st day after the last menstrual period, the all or nothing rule is considered to be valid. In other words, if the drug affects the embryo, it will result in miscarriage, if not, it is accepted that there is no harm. Usually, expectant mothers do not know that they are pregnant during this period and may use harmful medication. In this case, since the all-or-nothing rule applies, if the pregnancy continues, it is accepted that there is no problem. However, the period of organogenesis is considered a teratogenic period. This is the period between the 31st and 72nd day after the last menstrual period and if the drug used is teratogenic, it can be harmful to the fetus. To summarize what these categories mean:
A. No risk in controlled human study.
B. No evidence of risk in humans.
No human study, no risk in controlled animal study.
C. The risk cannot be eliminated.
No human study. There is a risk in a controlled animal study.
D. There is a positive risk.
There is a risk to humans. Potential benefits from the use of medicines may be considered if they outweigh the harm.
X. Contraindicated in pregnancy, i.e. cannot be used.